CAR T-Cell Therapy, an immunotherapy, is a novel therapy that programs a patient’s immune system to recognize and fight cancer. During the CAR T-Cell treatment process, T-Cells are drawn from a patient's blood and genetically modified to recognize the patient’s cancer cells when reinfused.

CAR T-Cell Therapy, an immunotherapy, is a novel therapy that programs a patient’s immune system to recognize and fight cancer. The immune system is responsible for ridding the body of abnormal cells that are foreign (like cancer) or infected. T-lymphocytes (T-Cells) are a type of cell responsible for killing abnormal cells. During the CAR T-Cell treatment process, T-Cells are drawn from a patient's blood and genetically modified to recognize the patient’s cancer cells when reinfused.

To schedule an appointment, call the Sarah Cannon Transplant and Cellular Therapy Program at Methodist Hospital at (210) 575-7800 or the Sarah Cannon Pediatric Transplant and Cellular Therapy Program at Methodist Hospital at (210) 575-2222.

What is CAR T-cell immunotherapy?

Here's how it works

  • First, a patient’s white blood cells are collected through a process called apheresis.
  • Then, the T-Cells are isolated from other blood cells.
  • T-Cells are then modified in a special facility to program them to recognize the cancer cells, what can be thought of as “fighter” T-Cells.
  • Lastly, the new “fighter” T-Cells are reinfused into the patient to target and kill the cancer.

CAR T-Cell therapy clinical trials

CAR T-Cell Therapy is an exciting new therapy that has been in research trials over the last few years. These types of treatments will be introduced gradually, and are available only at centers where doctors and nurses have been specially-trained and meet Foundation for Accreditation of Cellular Therapy (FACT) accreditation standards. Methodist Transplant Institute, a member of the Sarah Cannon Blood Cancer Network, the Cancer Institute of HCA Healthcare, has offered research options since 2015 and has clinical trials open in:

  • Mantle Cell NHL

A patient’s perspective

To learn more about clinical trials, CAR T-Cell Therapy (a type of immunotherapy), and potential treatment options for you, contact:

Methodist Transplant Institute
Adult Program: (210) 575-7800
Pediatric Program: (210) 575-2222